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Unusual Bacterial Behavior Discovered


Physical contact between Escherichia coli bacteria can trigger genes that halt the growth of one of the bacterium, a finding that is as exciting as it is surprising, according to scientists working under UCSB molecular biologist David Low.
“If bacteria can do this, then maybe we can (learn) to do it,” Low said. He suggested that the discovery by doctoral student Stephanie Aoki might open a door to managing chronic diseases, like urinary tract infections. “This has potential implications for new antibiotics.”
Aoki and her colleagues discovered what they call “contact-dependent inhibition of growth” while researching other aspects of E. coli. They worked for two years before identifying the two genes required for this behavior.
More information: <www.ia.ucsb.edu/pa/archive.aspx>.
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A Way to Deliver Micro-Drugs?
The high-precision “smart” bomb may someday have a microscopic counterpart in the “smart bio-nanotube” developed in the UCSB laboratories of materials scientist Cyrus Safinya and biochemist Leslie Wilson. By manipulating electrical charges on lipid membranes the lab teams found a way to self-assemble tiny capsules with ends that open or close on command.
“With either open ends or closed ends, these nanotubes could form the basis for controlled chemical and drug encapsulation and release,” said Safinya.
More information: <www.ia.ucsb.edu/pa/archive.aspx>.